Amitriptyline nanoparticle repositioning prolongs the anti-allodynic effect of enhanced microglia targeting.
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DOI: 10.1080/17435889.2024.2390349
Abstract: Aim: Amitriptyline (AMI) has been used to treat neuropathic pain. However, the clinical outcomes remain unsatisfactory, presumably due to a limited understanding of the underlying molecular mechanisms. Here, we investigated a drug repositioning strategy using… read more here.
Keywords: anti allodynic; ami nps; neuropathic pain; allodynic effect ... See more keywords