Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs.
Sign Up to like & getrecommendations! Published in 2020 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.0c00249
Abstract: ConspectusRNA-based technologies to control gene expression, such as RNA interference (RNAi) and CRISPR-Cas9, have become powerful tools in molecular biology and genomics. The exciting potential that RNAi and CRISPR-Cas9 may also become new therapeutic approaches… read more here.
Keywords: short interfering; rnai; amide linkages; backbone ... See more keywords