Aminopeptidase B can bioconvert L-type amino acid transporter 1 (LAT1)-utilizing amide prodrugs in the brain
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DOI: 10.3389/fphar.2022.1034964
Abstract: A prodrug approach is a powerful method to temporarily change the physicochemical and thus, pharmacokinetic properties of drugs. However, in site-selective targeted prodrug delivery, tissue or cell-specific bioconverting enzyme is needed to be utilized to… read more here.
Keywords: amide prodrugs; type amino; brain; acid transporter ... See more keywords