Amide Synthesis from Thiocarboxylic Acids and Amines by Spontaneous Reaction and Electrosynthesis.
Sign Up to like & getrecommendations! Published in 2019 at "ChemSusChem"
DOI: 10.1002/cssc.201900814
Abstract: Amide bond formation is one of the most important basic reactions in chemistry. A catalyst-free approach for constructing amide bonds from thiocarboxylic acids and amines was developed. The mechanistic studies showed that the disulfide was… read more here.
Keywords: acids amines; thiocarboxylic acids; chemistry; synthesis thiocarboxylic ... See more keywords
N‐Carboxyanhydrides (NCAs): Unorthodox and Useful Reagents for Amide Synthesis
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202301032
Abstract: N‐Carboxyanhydrides (NCAs) are compounds derived from the addition of a carboxylic acid to an isocyanate, and are known to form amides readily with the release of CO2 as a by‐product. NCAs have been known for… read more here.
Keywords: useful reagents; reagents amide; unorthodox useful; carboxyanhydrides ncas ... See more keywords
Automated and Parallel Amide Synthesis
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202401258
Abstract: Amide bonds are ubiquitous in molecules of interest such as pharmaceuticals, natural products, and agrochemicals. Over the last decades, significant efforts have been directed at developing efficient methods for the formation of this class of… read more here.
Keywords: parallel amide; methodology; chemistry; automated parallel ... See more keywords
Mild Amide Synthesis Using Nitrobenzene under Neutral Conditions.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01743
Abstract: Amide synthesis is one of the most important transformations in organic chemistry due to the broad application in pharmaceutical drugs and organic materials. In this report, we describe a mild protocol for amide formation using… read more here.
Keywords: synthesis using; amide synthesis; neutral conditions; using nitrobenzene ... See more keywords
Metal and Photocatalyst-Free Amide Synthesis via Decarbonylative Condensation of Alkynes and Photoexcited Nitroarenes.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c02513
Abstract: Depending on the intrinsic photoactivity of nitroarenes, we herein developed a practical Brønsted acid-catalyzed decarbonylative amide synthesis from alkynes and photoexcited nitroarenes without any metal or photocatalyst. This method exhibited compatibility with water and air,… read more here.
Keywords: alkynes photoexcited; photoexcited nitroarenes; metal photocatalyst; amide synthesis ... See more keywords
Rethinking the Dehydrogenative Amide Synthesis
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DOI: 10.1021/acscatal.7b02415
Abstract: This paper is concerned with the mechanism of the catalytic dehydrogenative coupling of primary alcohols with amines; it addresses the question on what happens to the aldehyde produced in the catalytic solution upon dehydrogenation of… read more here.
Keywords: amide synthesis; rethinking dehydrogenative; dehydrogenative amide;
Amide Synthesis via Aminolysis of Ester or Acid with an Intracellular Lipase
Sign Up to like & getrecommendations! Published in 2018 at "ACS Catalysis"
DOI: 10.1021/acscatal.8b02713
Abstract: A unique lipase (SpL) from Sphingomonas sp. HXN-200 was discovered as the first intracellular enzyme for the aminolysis of ester or acid to produce amide. Reactions of a series of esters and amines with SpL… read more here.
Keywords: ester acid; ester; lipase; aminolysis ester ... See more keywords
Atom-economic amide synthesis by using an iron-substituted polyoxometalate catalyst.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc05417a
Abstract: We report an efficient and economical amidation strategy by using a polyoxometalate-based iron catalyst that affords the corresponding amide products in good yields. All of the aliphatic, aromatic and heterocyclic substrates are produced in high… read more here.
Keywords: iron; atom economic; synthesis using; catalyst ... See more keywords
Biodegradable poly(urethane-urea-amide): Synthesis, characterization and mechanical studies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thermoplastic Composite Materials"
DOI: 10.1177/0892705720963537
Abstract: Biodegradable polyurethane with excellent mechanical property finds a lot of applications in the biomedical field. In this study, multi block copolymer poly(urethane-urea-amide) (PUUA) is prepared using polyethylene oxide, 1,6-hexamethylene diisocyanate and diamide (N1, N4-bis(6-aminohexyl)benzene-1,4-dicarboxamide (6T6)… read more here.
Keywords: urethane urea; biodegradable poly; hard segment; poly urethane ... See more keywords
Recent Advances in Visible-Light-Mediated Amide Synthesis
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DOI: 10.3390/molecules27020517
Abstract: Visible-light photoredox catalysis has attracted tremendous interest within the synthetic community. As such, the activation mode potentially provides a more sustainable and efficient platform for the activation of organic molecules, enabling the invention of many… read more here.
Keywords: light mediated; amide synthesis; advances visible; synthesis ... See more keywords