Iridium-Catalyzed Aerobic α,β-Dehydrogenation of γ,δ-Unsaturated Amides and Acids: Activation of Both α- and β-C-H bonds through an Allyl-Iridium Intermediate.
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DOI: 10.1021/jacs.7b11351
Abstract: Direct aerobic α,β-dehydrogenation of γ,δ-unsaturated amides and acids using a simple iridium/copper relay catalysis system is described. We developed a new strategy that overcomes the challenging issue associated with the low α-acidity of amides and… read more here.
Keywords: amides acids; unsaturated amides; iridium; dehydrogenation unsaturated ... See more keywords