Unified Approach to the Chemoselective α-Functionalization of Amides with Heteroatom Nucleophiles
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DOI: 10.1021/jacs.9b06956
Abstract: Functionalization at the α-position of carbonyl compounds has classically relied on enolate chemistry. As a result, the generation of a new C–X bond, where X is more electronegative than carbon requires an oxidation event. Herein… read more here.
Keywords: amides heteroatom; approach chemoselective; functionalization amides; chemoselective functionalization ... See more keywords