Nitrogen-directed unactivated γ-C(sp3)–H functionalization of amides toward 7-membered lactones via photoredox catalysis
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DOI: 10.1039/d4qo00564c
Abstract: Lactone motifs are prevalent in both naturally and synthetically bioactive molecules. We report herein a photoredox-catalyzed formal [5 + 2] annulation of O-acylhydroxamide derivatives with 1,3-dienes/1,3-enynes for rapid synthesis of... read more here.
Keywords: functionalization amides; sp3 functionalization; amides toward; nitrogen directed ... See more keywords