Synthesis of Polycyclic Amides via Tandem RhIII‐Catalyzed C−H Activation and Annulation from Dioxazolones and Alkynes
Sign Up to like & getrecommendations! Published in 2017 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.201700140
Abstract: A highly efficient synthesis of polycyclic amides by Rh(III)-catalyzed cascade cyclization of 3-phenyl-1, 4, 2-dioxazol-5-one and diphenylacetylene has been developed. This novel one-pot strategy expanded the application scope of directing groups to dioxazolones. read more here.
Keywords: amides via; polycyclic amides; synthesis polycyclic; via tandem ... See more keywords
Synthesis of α-Aryl Secondary Amides via Nickel-Catalyzed Reductive Coupling of Redox-Active Esters.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00918
Abstract: The transition-metal-catalyzed α-arylation of secondary amides remains a synthetic challenge due to the presence of a free N-H bond. We report a strategy to synthesize secondary α-aryl amides via a Ni-catalyzed reductive arylation of redox-active… read more here.
Keywords: secondary amides; redox active; amides via; catalyzed reductive ... See more keywords
Weak base-promoted selective rearrangement of oxaziridines to amides via visible-light photoredox catalysis.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc03855a
Abstract: The selective rearrangement of oxaziridines to amides via a single electron transfer (SET) pathway is unexplored. In this study, we present a weak base-promoted selective rearrangement of oxaziridines to amides via visible-light photoredox catalysis. The… read more here.
Keywords: amides via; rearrangement oxaziridines; weak base; selective rearrangement ... See more keywords
A three-component difunctionalization of N-alkenyl amides via organophotoredox radical-polar crossover.
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DOI: 10.1039/d2cc04101d
Abstract: Herein, we report a three-component organophotoredox coupling of N-alkenyl amides with α-bromocarbonyls and various nucleophiles. This transition metal-free difunctionalization protocol installs sequential C-C and C-Y (Y = S/O/N) bonds in alkenes. This reaction works with… read more here.
Keywords: amides via; difunctionalization; polar crossover; alkenyl amides ... See more keywords
N-Heterocyclic carbene (NHC)-catalyzed oxidation of unactivated aldimines to amides via imine umpolung under aerobic conditions
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra00897a
Abstract: Herein, we disclose an NHC-catalyzed aerobic oxidation of unactivated aldimines for the synthesis of amides via umpolung of imines proceeding through an aza-Breslow intermediate. We have developed an eco-friendly method for the conversion of imines… read more here.
Keywords: amides via; nhc catalyzed; unactivated aldimines; oxidation unactivated ... See more keywords