Ru(II)-catalyzed regioselective [4 + 1] redox-neutral spirocyclization of aryl amidines with diazopyrazolones: direct access to spiro[indole-3,4'-pyrazol]-5'-ones
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DOI: 10.1039/d3qo02071a
Abstract: An efficient protocol to construct spiro[indole-3,4'-pyrazol]-5'-ones via ruthenium(II)-catalyzed selective C-H bond activation/[4 + 1] spirocyclization starting from easily available N-aryl amidines and diazopyrazolones has been developed. A series of spiro-pyrazolones... read more here.
Keywords: indole pyrazol; amidines diazopyrazolones; spiro indole; aryl amidines ... See more keywords