Synthesis, Antiproliferative Evaluation and QSAR Analysis of Novel Halogen- and Amidino-Substituted Benzothiazoles and Benzimidazoles
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DOI: 10.3390/ijms232415843
Abstract: Syntheses of 6-halogen-substituted benzothiazoles were performed by condensation of 4-hydroxybenzaldehydes and 2-aminotiophenoles and subsequent O-alkylation with appropriate halides, whereas 6-amidino-substituted benzothiazoles were synthesized by condensation of 5-amidino-2-aminothiophenoles and corresponding benzaldehydes. While most of the compounds… read more here.
Keywords: halogen; cell; substituted benzothiazoles; amidino ... See more keywords
Biological Activity of Amidino-Substituted Imidazo [4,5-b]pyridines
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DOI: 10.3390/molecules28010034
Abstract: A series of cyano- and amidino-substituted imidazo[4,5-b]pyridines were synthesized using standard methods of organic synthesis, and their biological activity was evaluated. Biological evaluation included in vitro assessment of antiproliferative effects on a diverse selection of… read more here.
Keywords: imidazo pyridines; amidino; biological activity; activity ... See more keywords
Synthesis and antioxidative potency of novel amidino substituted benzimidazole and benzothiazole derivatives
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DOI: 10.5562/cca3146
Abstract: Herein we present the synthesis of versatile amidino substituted benzothiazole 3-10 and benzimidazole 12-19 derivatives substituted with the variable number of hydroxy and methoxy groups. Furthermore, the synthesized compounds were explored for their antioxidative activity… read more here.
Keywords: synthesis antioxidative; antioxidative activity; antioxidative potency; amidino ... See more keywords