Amifostine protects from the peripheral sensory neuropathy induced by oxaliplatin in mice
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x202010263
Abstract: Sensory neuropathy is a dose-limiting side effect of oxaliplatin-based cancer treatment. This study investigated the antinociceptive effect of amifostine and its potential neuroprotective mechanisms on the oxaliplatin-related peripheral sensory neuropathy in mice. Oxaliplatin (1 mg/kg)… read more here.
Keywords: mice; peripheral sensory; sensory neuropathy; amifostine ... See more keywords
Three-Dimensional Cell Metabolomics Deciphers the Anti-Angiogenic Properties of the Radioprotectant Amifostine
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13122877
Abstract: Simple Summary Cancer and inflammation share aberrant angiogenesis as a hallmark, and, thus, anti-angiogenetic strategies remain of key interest. Amifostine, which is already a drug on the market, may be of further benefit to patients… read more here.
Keywords: angiogenesis; cell metabolomics; angiogenic properties; anti angiogenic ... See more keywords
The radioprotective role of amifostine on osteointegration of titanium implants in the tibia of rats: an animal study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.23023
Abstract: Background Titanium is the most widely used metal for bone integration, especially for cancer patients receiving ionizing radiation. This study aimed to investigate the amifostine administration that would reduce the effects of radiation on bone… read more here.
Keywords: titanium implants; amifostine; amf imp; radiation ... See more keywords