Novel amikacin resistance genes identified from human gut microbiota by functional metagenomics
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DOI: 10.1111/jam.15615
Abstract: The aim of this study was to evaluate the diversity and potential for horizontal transfer of amikacin resistance genes from the human gut. read more here.
Keywords: resistance genes; amikacin resistance; genes identified; novel amikacin ... See more keywords
Phenotypic amikacin resistance may not indicate poor response to amikacin in Mycobacterium avium complex pulmonary disease
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DOI: 10.1128/aac.00084-24
Abstract: ABSTRACT When using amikacin to treat Mycobacterium avium complex pulmonary disease (MAC-PD), a minimum inhibitory concentration resistance breakpoint of ≥64 mcg/mL is recommended. We explored whether amikacin resistance characterized by phenotypic drug susceptibility testing was… read more here.
Keywords: resistance; mycobacterium avium; amikacin resistance; avium complex ... See more keywords
Investigation of in vitro susceptibility and resistance mechanisms to amikacin among diverse carbapenemase-producing Enterobacteriaceae
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DOI: 10.1186/s12920-024-02016-0
Abstract: This study aims to assess the in vitro drug susceptibility of various Carbapenemase-Producing Enterobacteriaceae (CPE) genotypes and elucidate the underlying mechanisms of amikacin resistance. A total of 72 unique CPE strains were collected from the… read more here.
Keywords: resistance; producing enterobacteriaceae; carbapenemase producing; cpe ... See more keywords