Articles with "aminal intermediates" as a keyword



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C-H Functionalization of Peptides via Cyclic Aminal Intermediates.

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Published in 2021 at "Organic letters"

DOI: 10.1021/acs.orglett.1c02041

Abstract: Protected dipeptides can be converted into cyclic ketoaminals, which can be subjected to palladium-catalyzed regioselective C-H functionalization. The best results are obtained using the 2-(methylthio)aniline (MTA) directing group, which is superior to the commonly used… read more here.

Keywords: peptides via; via cyclic; aminal intermediates; cyclic aminal ... See more keywords