Copper-catalyzed enantioselective direct α-C-H amination of β-dicarbonyl derivatives with aryl hydroxylamines and mechanistic insights
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DOI: 10.1016/j.mcat.2020.111067
Abstract: Abstract We report a novel and efficient Cu-catalyzed direct asymmetric amination of tertiary β-carbonyl compounds using aryl hydroxylamine as electrophilic nitrogen donor. The process facilitates the convenient and direct synthesis of chiral α-amino carbonyl derivatives,… read more here.
Keywords: direct amination; amination dicarbonyl; catalyzed enantioselective; enantioselective direct ... See more keywords