Reductive amination of ketones with ammonium catalyzed by a newly identified Brevibacterium epidermidis strain for the synthesis of (S)-chiral amines
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DOI: 10.1016/s1872-2067(18)63108-0
Abstract: Abstract The asymmetric reductive amination of achiral ketones with ammonia is a particularly attractive reaction for the synthesis of chiral amines. Although several engineered amine dehydrogenases have been developed by protein engineering for the asymmetric… read more here.
Keywords: synthesis chiral; chiral amines; amination ketones; reductive amination ... See more keywords
Electrochemical, Iodine-Mediated α-CH Amination of Ketones by Umpolung of Silyl Enol Ethers.
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DOI: 10.1021/acs.orglett.0c02068
Abstract: The electrochemical, oxidative Umpolung reaction of silyl enol ethers utilizing simple iodide salts for the synthesis of α-amino ketones is described. The products were isolated in excellent yields of up to 100%, and various functionalized… read more here.
Keywords: silyl enol; electrochemical iodine; enol ethers; mediated amination ... See more keywords
Direct catalytic enantioselective amination of ketones for the formation of tri- and tetrasubstituted stereocenters† †Electronic supplementary information (ESI) available: Experimental details, and characterization data. See DOI: 10.1039/c8sc00147b
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DOI: 10.1039/c8sc00147b
Abstract: A Zn–ProPhenol catalyzed direct amination of α-branched and unbranched ketones produces α-amino carbonyl and β-amino alcohol products. read more here.
Keywords: catalytic enantioselective; direct catalytic; ketones formation; amination ketones ... See more keywords