Solvent-free Buchwald–Hartwig amination with low palladium loadings
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DOI: 10.1016/j.mencom.2017.11.027
Abstract: A highly efficient ‘green’ solvent-free monoarylation of primary anilines with aryl bromides mediated by the expanded-ring N-heterocyclic carbene palladium complex (THP-Dipp)Pd(cinn)Cl [THP-Dipp is 1,3-bis(2,6-diisopropylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene; cinn is cinnamyl] can be performed at low catalyst loadings (0.1… read more here.
Keywords: amination low; hartwig amination; buchwald hartwig; free buchwald ... See more keywords