ω‐(5‐Phenyl‐2H‐tetrazol‐2‐yl)alkyl‐substituted hydrazides and related compounds as inhibitors of amine oxidase copper containing 3 (AOC3)
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200111
Abstract: Amine oxidase copper containing 3 (AOC3), also known as plasma amine oxidase, semicarbazide‐sensitive amine oxidase, or vascular adhesion protein‐1, catalyzes the oxidative deamination of primary amines to aldehydes using copper and a quinone as cofactors.… read more here.
Keywords: copper; oxidase copper; phenyl tetrazol; copper containing ... See more keywords
Amine oxidase from Euphorbia characias: Kinetic and structural characterization
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1612
Abstract: This minireview focuses on a plant copper/2,4,5‐trihydroxyphenyl alanine quinone amine oxidase isolated from the latex of the shrub Euphorbia characias (ELAO). This enzyme has been investigated in terms of both molecular structure and kinetic mechanism.… read more here.
Keywords: structural characterization; amine; amine oxidase; euphorbia characias ... See more keywords
Inactivation of bovine plasma amine oxidase by 1,1,1-trihalo-3-aminopropanes.
Sign Up to like & getrecommendations! Published in 2017 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2017.10.007
Abstract: In this paper, we report the inactivation of copper containing bovine plasma amine oxidase (BPAO) by a series of saturated alkylamines containing halogen atoms at γ-position, which are 1,1,1-trihalo-3-aminopropane, 1,1,1-trifluoro-2-hydroxy-3-aminopropane, 1,1,1-trichloro-2-hydroxy-3-aminopropane, and 1,1,1-trichloro-2-(2-phenethyloxy)-3-aminopropane. The trihalo-2-hydroxypropylamine… read more here.
Keywords: plasma amine; amine oxidase; bovine plasma; aminopropane ... See more keywords
Enzymatic production of 4-hydroxyphenylacetaldehyde by oxidation of the amino group of tyramine with a recombinant primary amine oxidase
Sign Up to like & getrecommendations! Published in 2020 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2020.03.007
Abstract: Abstract In this study, an efficient enzymatic process for the synthesis of 4-hydroxyphenylacetaldehyde (4-HPAA) from tyramine was developed using whole cells of recombinant Escherichia coli co-expressing primary amine oxidase (PrAO) from E. coli and catalase… read more here.
Keywords: amine oxidase; tyramine; yield; primary amine ... See more keywords
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.2c00559
Abstract: Natural polyamines (PAs) are key players in cellular homeostasis by regulating cell growth and proliferation. Several observations highlight that PAs are also implicated in pathways regulating cell death. Indeed, the PA accumulation cytotoxic effect, maximized… read more here.
Keywords: synthesis biological; biological evaluation; synthesis; bovine serum ... See more keywords
Unprecedented Copper(II) Complex with a Topoquinone-like Moiety as a Structural and Functional Mimic for Copper Amine Oxidase: Role of Copper(II) in the Genesis and Amine Oxidase Activity
Sign Up to like & getrecommendations! Published in 2019 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b02326
Abstract: Copper amine oxidase (CAO), consisting of the topoquinone (TPQ) cofactor, catalyzes the oxidation of primary amines to aldehyde. We have successfully addressed this issue through isolation of a cop... read more here.
Keywords: amine oxidase; copper amine; copper; topoquinone ... See more keywords
Synthesis of Furo-/Thieno-Quinolines using an Amine Oxidase-Inspired Catalyst
Sign Up to like & getrecommendations! Published in 2023 at "Synlett"
DOI: 10.1055/a-2103-9629
Abstract: Herein, we report the regioselective synthesis of furo-/thieno quinolines using an amine oxidase-inspired catalyst (1,10-phenanthroline-5,6-dione, phd) and an abundant Lewis acid (FeCl3) as a cocatalyst. The aerobic amine dehydrogenation proceeds at milder conditions and produces… read more here.
Keywords: furo thieno; quinolines using; synthesis furo; using amine ... See more keywords
Copper amine oxidase 8 regulates arginine-dependent nitric oxide production in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erx105
Abstract: Highlight Copper amine oxidase in polyamine metabolism modulates arginine-dependent nitric oxide production by affecting arginase activity in Arabidopsis thaliana. read more here.
Keywords: amine oxidase; dependent nitric; copper amine; oxide production ... See more keywords
Zinc-α2-glycoprotein as an inhibitor of amine oxidase copper-containing 3
Sign Up to like & getrecommendations! Published in 2020 at "Open Biology"
DOI: 10.1098/rsob.190035
Abstract: Zinc-α2-glycoprotein (ZAG) is a major plasma protein whose levels increase in chronic energy-demanding diseases and thus serves as an important clinical biomarker in the diagnosis and prognosis of the development of cachexia. Current knowledge suggests… read more here.
Keywords: amine oxidase; copper containing; zag; oxidase copper ... See more keywords
Theobromine and related methylxanthines as inhibitors of Primary Amine Oxidase.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.12697
Abstract: Methylxanthines are among the most widely consumed drugs in the world and evidence of their health benefits has been growing in recent years. Primary Amine Oxidase (PrAO) has been recognized as a therapeutic target for… read more here.
Keywords: health; prao; primary amine; amine oxidase ... See more keywords
Evaluation of the Expression of Amine Oxidase Proteins in Breast Cancer
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18122775
Abstract: We aimed to evaluate the expression of amine oxidase proteins in breast cancer and their clinical implications. We performed immunohistochemical staining of amine oxidase proteins (LOX, lysyl oxidase, AOC3, amine oxidase, MAOA, monoamine oxidase A,… read more here.
Keywords: amine oxidase; expression; mao; breast cancer ... See more keywords