A Chiral Amine Transfer Approach to the Photocatalytic Asymmetric Synthesis of α-Trialkyl-α-tertiary Amines
Sign Up to like & getrecommendations! Published in 2023 at "Organic Letters"
DOI: 10.1021/acs.orglett.2c04308
Abstract: A long-standing challenge within radical chemistry is that of controlling the absolute stereochemistry of the products. Here, we report the stereocontrolled addition of α-amino radicals reductively generated from imines via visible-light-mediated photoredox-catalysis to alkenes, giving… read more here.
Keywords: tertiary amines; transfer approach; chiral amine; trialkyl tertiary ... See more keywords
Unprotected amine transfer performed by non-heme iron(II) complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04992a
Abstract: Direct amination of C-H or CC bonds using unprotected amino groups is very challenging, especially with earth abundant metal ions. Here we show that a bioinspired iron(II) complex catalyses the double amination of its dangling… read more here.
Keywords: performed non; unprotected amine; non heme; iron ... See more keywords