Regioselective Synthesis of Multifunctional Allylic Amines; Access to Ambiphilic Aziridine Scaffolds.
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DOI: 10.1021/acs.orglett.1c01398
Abstract: We describe, for the first time, a highly regioselective hydrosilylation of propargylic amines. The reaction utilizes a PtCl2/XantPhos catalyst system to deliver hydrosilanes across the alkyne to afford multifunctional allylic amines in high yields. The… read more here.
Keywords: multifunctional allylic; amines access; allylic amines; synthesis multifunctional ... See more keywords