Regioselective Synthesis of Multifunctional Allylic Amines; Access to Ambiphilic Aziridine Scaffolds.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01398
Abstract: We describe, for the first time, a highly regioselective hydrosilylation of propargylic amines. The reaction utilizes a PtCl2/XantPhos catalyst system to deliver hydrosilanes across the alkyne to afford multifunctional allylic amines in high yields. The… read more here.
Keywords: multifunctional allylic; amines access; allylic amines; synthesis multifunctional ... See more keywords
I2-Promoted oxidative annulation of three different amines to access diverse biheteroaryls
Sign Up to like & getrecommendations! Published in 2024 at "Organic Chemistry Frontiers"
DOI: 10.1039/d4qo01801j
Abstract: Utilizing tertiary alkylamines as reliable two-carbon building blocks, a concise and efficient route for the regioselective synthesis of biquinolines from 2-methylquinolines and arylamines has been established. This I2-promoted approach enables... read more here.
Keywords: annulation three; amines access; promoted oxidative; three different ... See more keywords