Protein and Amino Acid Adequacy and Food Consumption by Processing Level in Vegans in Brazil
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.18226
Abstract: This cross-sectional survey study compares protein and essential amino acid intake levels against recommended levels among individuals in Brazil who adhere to a vegan diet and assesses whether adequate protein consumption is associated with greater… read more here.
Keywords: consumption; amino; acid adequacy; amino acid ... See more keywords
Mutational analyses identify a single amino acid critical for colour tuning in proteorhodopsins
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14297
Abstract: Microbial rhodopsins are light‐activated proteins that contain seven transmembrane alpha‐helices. Spectral tuning in microbial rhodopsins is a useful optogenetic tool. In this study, we report a new site that controls spectral tuning. In the proteorhodopsins… read more here.
Keywords: single amino; amino acid; spectral tuning; tuning proteorhodopsins ... See more keywords
GCN2 kinase-mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln (CUG) charging under amino acid starvation.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14628
Abstract: Each tRNA is aminoacylated (charged) with a genetic codon-specific amino acid. It remains unclear what factors are associated with tRNA charging and how tRNA charging is maintained. By using the individual tRNA acylation PCR (i-tRAP)… read more here.
Keywords: glutamine level; acid starvation; cug; amino acid ... See more keywords
Characterization and multifunctionality of two amino acid aminotransferases from the hyperthermophile Thermotoga maritima
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DOI: 10.1002/1873-3468.70034
Abstract: The hyperthermophile Thermotoga maritima possesses a unique peptidoglycan containing an unusual d‐lysine. Previously, we identified enzymes involved in the production of d‐lysine and d‐glutamate, respectively, but the biosynthetic pathway of d‐alanine remains unclear. Herein, we… read more here.
Keywords: acid aminotransferases; hyperthermophile thermotoga; thermotoga maritima; amino ... See more keywords
CSF amino acid profiles in ICV‐streptozotocin‐induced sporadic Alzheimer's disease in male Wistar rat: a metabolomics and systems biology perspective
Sign Up to like & getrecommendations! Published in 2024 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13814
Abstract: Alzheimer's disease (AD) is an increasingly important public health concern due to the increasing proportion of older individuals within the general population. The impairment of processes responsible for adequate brain energy supply primarily determines the… read more here.
Keywords: alzheimer disease; biology; amino acid; acid ... See more keywords
Engineering a Single Amino Acid Bionanozyme for Ultrasensitive Detection of Biomarkers: A WHO‐REASSURE‐ Aligned Approach
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202502902
Abstract: The development of advanced biosensing materials that adhere to the WHO‐REASSURE standards is crucial in resource‐constrained environments. Conventional peroxidase (POD) enzymes, essential for sensitive and selective colorimetric assays, encounter challenges such as high production costs,… read more here.
Keywords: detection; single amino; acid bionanozyme; detection biomarkers ... See more keywords
Amino Acid‐Decorated MOF Membranes Toward Facilitated CO2 Separation Under Varying Humidities
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DOI: 10.1002/adfm.202506327
Abstract: Although proven to be promising for CO2 capture from flue gas, maintaining superior separation efficiency of CO2‐philic membranes under widely differing humidities remains highly challenging to date. Targeting high‐efficiency and humidity‐resistant flue gas separation, in… read more here.
Keywords: mil 140a; separation; amino acid; co2 ... See more keywords
Amino‐Acid‐Encoded Supramolecular Photothermal Nanomedicine for Enhanced Cancer Therapy
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DOI: 10.1002/adma.202200139
Abstract: Photothermal nanomedicine based on self‐assembly of biological components, with excellent biosafety and customized performance, is vital significance for precision cancer therapy. However, the programmable design of photothermal nanomedicine remains extremely challenging due to the vulnerability… read more here.
Keywords: photothermal nanomedicine; cancer therapy; amino acid;
Self‐Assembled Ruthenium–Amino Acid Conjugates Enable Endoplasmic Reticulum–Nucleus Cascade Targeting for Cell Pyroptosis and DNA Destruction
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202508713
Abstract: The distinct photophysical and photochemical properties of ruthenium (Ru) complexes have made them potent therapeutic agents in photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) for tumors. Simple synthesis, precise self‐assembly delivery and specific subcellular distribution… read more here.
Keywords: amino acid; cascade targeting; endoplasmic reticulum; ruthenium ... See more keywords
A Metabolic Reprogramming Amino Acid Polymer as an Immunosurveillance Activator and Leukemia Targeting Drug Carrier for T‐Cell Acute Lymphoblastic Leukemia
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DOI: 10.1002/advs.202104134
Abstract: Abstract Compromised immunosurveillance leads to chemotherapy resistance and disease relapse of hematological malignancies. Amino acid metabolism regulates immune responses and cancer; however, a druggable amino acid metabolite to enhance antitumor immunosurveillance and improve leukemia targeting‐therapy… read more here.
Keywords: immunosurveillance; cell; leukemia; metabolic reprogramming ... See more keywords
Unnatural Amino Acid‐Based Ionic Liquid Enables Oral Treatment of Nonsense Mutation Disease in Mice
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DOI: 10.1002/advs.202306792
Abstract: This investigation addresses the challenge of suboptimal unnatural amino acid (UAA) utilization in the site‐specific suppression of nonsense mutations through genetic code expansion, which is crucial for protein restoration and precise property tailoring. A facile… read more here.
Keywords: liquid; nonsense mutation; treatment nonsense; amino acid ... See more keywords