Polyamines interfere with protein ubiquitylation and cause depletion of intracellular amino acids: a possible mechanism for cell growth inhibition
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13299
Abstract: Spermidine is a polyamine present in eukaryotes with essential functions in protein synthesis. At high concentrations spermidine and norspermidine inhibit growth by unknown mechanisms. Transcriptomic analysis of the effect of norspermidine on the plant Arabidopsis… read more here.
Keywords: amino acids; protein ubiquitylation; growth inhibition; depletion ... See more keywords
Mutational analysis of Yih1 and IMPACT reveals amino acids required for Gcn2 inhibition
Sign Up to like & getrecommendations! Published in 2025 at "FEBS Letters"
DOI: 10.1002/1873-3468.70148
Abstract: In response to amino acid starvation, the protein kinase Gcn2 phosphorylates the eukaryotic translation initiation factor eIF2α, allowing cells to adapt to adverse conditions. Gcn2 function requires direct binding to effector protein Gcn1 via the… read more here.
Keywords: gcn2 inhibition; amino acids; mutational analysis; impact ... See more keywords
Mechanomorphogenic Films Formed via Interfacial Assembly of Fluorinated Amino Acids
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202104223
Abstract: Nature has evolved several elegant strategies to organize inert building blocks into adaptive supramolecular structures. Favored among these is interfacial self‐assembly, where the unique environment of liquid–liquid junctions provides structural, kinetic, thermodynamic, and chemical properties… read more here.
Keywords: formed via; assembly; amino acids; films formed ... See more keywords
Synergistic Photoluminescence Enhancement in Nonaromatic Amino Acids and Sugars via Glycosylation
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202423603
Abstract: Nonaromatic amino acids with intrinsic photoluminescence (PL) have drawn growing attention due to their crucial role in the luminescence of natural proteins. However, the weak luminescence significantly constrains the study of specific photophysical processes, emission… read more here.
Keywords: enhancement; amino acids; nonaromatic amino; acids sugars ... See more keywords
Nature-Inspired Circular-Economy Recycling for Proteins: Proof of Concept.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202104581
Abstract: The billion tons of synthetic-polymer-based materials (i.e. plastics) produced yearly are a great challenge for humanity. Nature produces even more natural polymers, yet they are sustainable. Proteins are sequence-defined natural polymers that are constantly recycled… read more here.
Keywords: recycling proteins; amino acids; nature inspired; circular economy ... See more keywords
Tuning the Magnetization of Manganese (II) Carbonate by Intracrystalline Amino Acids
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202201652
Abstract: Incorporation of organic molecules into the lattice of inorganic crystalline hosts is a common phenomenon in biomineralization and is shown to alter various properties of the crystalline host. Taking this phenomenon as a source of… read more here.
Keywords: amino acids; magnetization manganese; manganese carbonate; tuning magnetization ... See more keywords
JA‐Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8‐SlWRKY57‐SlAVT6s Module in Tomato
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202416717
Abstract: A crucial strategy employed by plants to enhance insect resistance is allocating amino acids into secondary metabolic pathways, ensuring the synthesis of specialized metabolites that confer resistance. The storage and redistribution of amino acids primarily… read more here.
Keywords: resistance; amino acids; acid homeostasis; amino ... See more keywords
Amino acids as fertilizer for agronomic crops: The next green revolution?
Sign Up to like & getrecommendations! Published in 2025 at "Agronomy Journal"
DOI: 10.1002/agj2.70145
Abstract: This study sought to determine whether organic N in the form of amino acids could be used as a replacement for synthetic inorganic N fertilizer for growing an agronomic crop, and if so, would there… read more here.
Keywords: green revolution; corn; next green; amino acids ... See more keywords
Green and one‐pot surface coating of iron oxide magnetic nanoparticles with natural amino acids and biocompatibility investigation
Sign Up to like & getrecommendations! Published in 2018 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.4069
Abstract: We report the synthesis of iron oxide magnetic nanoparticles (IONPs) coated with various natural amino acids (AAs) using a one-pot reaction in an aqueous medium. Several AAs, which contained hydrophilic and hydrophobic groups, were selected… read more here.
Keywords: natural amino; amino acids; iron oxide; magnetic nanoparticles ... See more keywords
An efficient cell‐free protein synthesis platform for producing proteins with pyrrolysine‐based noncanonical amino acids
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Journal"
DOI: 10.1002/biot.202200096
Abstract: Incorporation of noncanonical amino acids (ncAAs) into proteins opens new opportunities in biotechnology and synthetic biology. Pyrrolysine (Pyl)‐based ncAAs are some of the most predominantly used, but expression systems suffer from low yields. Here, we… read more here.
Keywords: amino acids; platform; synthesis; noncanonical amino ... See more keywords
N‐methylation in amino acids and peptides: Scope and limitations
Sign Up to like & getrecommendations! Published in 2018 at "Biopolymers"
DOI: 10.1002/bip.23110
Abstract: Active pharmaceutical ingredients (APIs) can be divided into two types, namely chemical and biological entities. Traditionally, the former has been associated with the so‐called small molecules. The revival of peptides in pharmaceutical industry results from… read more here.
Keywords: peptide; amino acids; methylation amino; acids peptides ... See more keywords