Evaluating the Pharmacokinetics and Systemic Effects of a Permeability Enhancer Sodium N-[8-(2-hydroxybenzoyl)amino] caprylate in Rats.
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DOI: 10.1016/j.xphs.2020.04.016
Abstract: Oral administration is the preferred route for drug delivery and its success is highly dependent on a compound's ADME properties, of which, permeability plays a major role. Therefore, permeability enhancers are an attractive area of… read more here.
Keywords: permeability enhancer; systemic effects; hydroxybenzoyl amino; amino caprylate ... See more keywords
Development and In Vitro and In Vivo Evaluation of Microspheres Containing Sodium N-[8-(2-hydroxybenzoyl)amino]caprylate for the Oral Delivery of Berberine Hydrochloride
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DOI: 10.3390/molecules25081957
Abstract: Microspheres containing absorption enhancer (sodium N-[8-(2-hydroxybenzoyl)amino]caprylate, SNAC) were developed to enhance the oral bioavailability of berberine hydrochloride (BER) with poor intestinal membrane permeability. Microspheres were prepared and characterized by particle size measurements, scanning electron microscopy,… read more here.
Keywords: hydroxybenzoyl amino; amino caprylate; microspheres containing; ber ... See more keywords