Four-Component Synthesis of 2-Amino-3-Cyanopyridine Derivatives Catalyzed by Cu@imineZCMNPs as a Novel, Efficient and Simple Nanocatalyst Under Solvent-Free Conditions
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DOI: 10.1007/s10562-018-2318-3
Abstract: An efficient and convenient method was investigated for synthesis of 2-amino-3-cyanopyridine derivatives via a one-pot four-component reaction of various types of aldehydes, acetophenone, malononitrile, and ammonium acetate in the presence of 10 mg Cu@imineZCMNPs catalyst. The… read more here.
Keywords: four component; microscopy; synthesis amino; amino cyanopyridine ... See more keywords
Antibacterial activity of 2-amino-3-cyanopyridine derivatives
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DOI: 10.1016/j.mencom.2020.07.031
Abstract: New 2-amino-4-aryl-3-cyanopyridines were obtained by the three-component condensation of arylidenemalononitriles, malononitrile and (di)amine system or acetoacetanilide. Antibacterial activity of all synthesized compounds against the Gram-negative bacteria E. coli and the Gram-positive B. subtilis was tested,… read more here.
Keywords: amino; activity amino; antibacterial activity; amino cyanopyridine ... See more keywords