Synthesis of α-Amino Cyclobutanones via Formal 1,3-Hydroxy Migration Triggered by Formation of α-Imino Rhodium Carbene.
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DOI: 10.1021/acs.orglett.2c01029
Abstract: Formal intramolecular 1,3-OH migration of α-imino carbene was achieved producing a unique zwitterion, and the subsequent selective annulation afforded α-amino cyclobutanone. Features such as readily available substrates, mild reaction conditions, a time-saving procedure, excellent functional… read more here.
Keywords: migration; cyclobutanones via; imino; amino cyclobutanones ... See more keywords