Cross-linked PMMA-based bifunctional amino derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thermal Analysis and Calorimetry"
DOI: 10.1007/s10973-018-7764-z
Abstract: The main purpose of the present study is to investigate the role of 1,12-diaminododecane and 4,4′-diaminobiphenyl, as bifunctional amino derivatives, on the properties of poly(methyl methacrylate) (PMMA). Cross-linked PMMA derivatives of different degrees (2, 5,… read more here.
Keywords: amino derivatives; cross linked; cross; bifunctional amino ... See more keywords
Synthesis and Molecular Docking of Some Grossgemin Amino Derivatives as Tubulin Inhibitors Targeting Colchicine Binding Site
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Chemistry"
DOI: 10.1155/2021/5586515
Abstract: Six amino derivatives of grossgemin (2–7) were synthesized according to the reported essential pharmacophoric features of colchicine binding site inhibitors (CBSIs). The derivatives 4–6 were obtained for the first time. The pharmacophoric features of 2–7… read more here.
Keywords: amino derivatives; binding site; colchicine binding; colchicine ... See more keywords
13-amino derivatives of dehydrocostus lactone display greatly enhanced selective toxicity against breast cancer cells and improved binding energies to protein kinases in silico
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271389
Abstract: The biological activities of dehydrocostus lactone and its analogues are suggested to be mediated by the lactone ring and α,β-methylene-γ-lactone. However, few studies exist on the structure-activity relationship of 13-amino derivatives of dehydrocostus latone. In… read more here.
Keywords: breast cancer; dehydrocostus lactone; amino derivatives; lactone ... See more keywords
Amino Derivatives of Diaryl Pyrimidines and Azolopyrimidines as Protective Agents against LPS-Induced Acute Lung Injury
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DOI: 10.3390/molecules28020741
Abstract: The problem of lung damage originating from excessive inflammation and cytokine release during various types of infections remains relevant and stimulates the search for highly effective and safe drugs. The biological activity of the latter… read more here.
Keywords: derivatives diaryl; acute lung; amino derivatives; lung injury ... See more keywords
Toward Pathogenic Biofilm Suppressors: Synthesis of Amino Derivatives of Pillar[5]arene and Supramolecular Assembly with DNA
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020476
Abstract: New amino derivatives of pillar[5]arene were obtained in three stages with good yields. It was shown that pillar[5]arene containing thiaether and tertiary amino groups formed supramolecular complexes with low molecular weight model DNA. Pillar[5]arene formed… read more here.
Keywords: dna; derivatives pillar; pillar arene; biofilm ... See more keywords