Delivery of Anti-microRNA-712 to Inflamed Endothelial Cells Using Poly(β-amino ester) Nanoparticles Conjugated with VCAM-1 Targeting Peptide.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001894
Abstract: Endothelial cells (ECs) are an important target for therapy in a wide range of diseases, most notably atherosclerosis. Developing efficient nanoparticle (NP) systems that deliver RNA interference (RNAi) drugs specifically to dysfunctional ECs in vivo… read more here.
Keywords: mir 712; anti microrna; endothelial cells; amino ester ... See more keywords
Gamma irradiation, thermal conductivity, and phase change tests of the cement‐hyperbranched poly amino‐ester‐block‐poly cabrolactone‐polyurathane plaster‐lead oxide and arsenic oxide composite for development of radiation shielding material
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Energy Research"
DOI: 10.1002/er.7136
Abstract: The work which has been done on cement‐polymer composite based shielding materials was comprehensively described in the present article, the choice of the study presented here is based on the choice of the researches. The… read more here.
Keywords: block poly; ester block; poly amino; poly ... See more keywords
Hybrid Phosphine/Amino‐Acid Ligands Built on Phenyl and Ferrocenyl Platforms: Application in the Suzuki Coupling of o‐Dibromobenzene with Fluorophenylboronic Acid
Sign Up to like & getrecommendations! Published in 2023 at "ChemistryOpen"
DOI: 10.1002/open.202200190
Abstract: Abstract We describe the synthesis and characterization of two classes of hybrid phosphino ligands functionalized with amino ester or amino acid groups. These compounds are built either on a rigid planar phenyl platform or on… read more here.
Keywords: acid; amino acid; fluorophenylboronic acid; amino ester ... See more keywords
Kinetic model development for α-amino ester hydrolase (AEH) catalyzed synthesis of β-lactam antibiotics
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.131816
Abstract: Abstract α-Amino ester hydrolases (AEH) are a class of enzymes highly specific for catalyzing the synthesis and hydrolysis of amides and esters of α-amino acids. They are particularly promising catalyst candidates as an alternative to… read more here.
Keywords: substrate inhibition; synthesis; aeh catalyzed; model ... See more keywords
Hertzian elasticity and triggered swelling kinetics of poly(amino ester)-based gel beads with controlled hydrophilicity and functionality: A mild and convenient synthesis via dropwise freezing into cryogenic liquid
Sign Up to like & getrecommendations! Published in 2019 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2019.02.018
Abstract: Abstract Poly(amino ester)-based homo- and co-polymeric gel beads were prepared via “dropwise freezing into cryogenic liquid” method and multi-responsive properties of the prepared spherical beads were confirmed by the pulsatile swelling kinetics and the stress-strain… read more here.
Keywords: gel beads; gel; poly amino; amino ester ... See more keywords
Biocompatible fluorinated poly(β-amino ester)s for safe and efficient gene therapy.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.11.015
Abstract: Cationic polymers have been widely used as one of the most promising non-viral vehicles for gene delivery due to their potential safety and ease of large-scale production. Here, we report the design and synthesis of… read more here.
Keywords: fluorinated poly; ester; amino ester; poly amino ... See more keywords
Design, synthesis, and properties of novel amino-ester and amino-ester-alcohol polymer backbones
Sign Up to like & getrecommendations! Published in 2019 at "Polymer"
DOI: 10.1016/j.polymer.2019.121663
Abstract: Abstract Simultaneous polymerization of polyacrylic, polyamine, and polyepoxy monomers offers the potential to generate a novel polymer backbone with new and beneficial properties. The Aza-Michael addition of amines to acrylates is fast and exothermic and… read more here.
Keywords: polymer backbones; ester alcohol; alcohol polymer; amino ester ... See more keywords
Effects of Kinetic Chain Length on the Degradation of Poly(β-amino ester)-Based Networks and Use in 3D Printing by Projection Microstereolithography.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00362
Abstract: Poly(β-amino ester)-diacrylates (PBAE-dAs) are promising resins for three-dimensional (3D) printing. This study investigated the degradation of two PBAEs with different chemistries and kinetic chain lengths. PBAE-dA monomers were synthesized from benzhydrazide and poly(ethylene glycol) (A6)… read more here.
Keywords: degradation; amino ester; kinetic chain; chain ... See more keywords
Synthesis and Characterization of Quaternized Poly(β-amino ester) for Highly Efficient Delivery of Small Interfering RNA.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00549
Abstract: The development of non-viral vectors for gene delivery has gained attention over the past decades. Specifically, poly(β-amino ester) (PBAE) has shown great potential for improving the delivery of gene therapeutics. It has been observed that… read more here.
Keywords: delivery; amino ester; poly amino; gene ... See more keywords
Manipulation of Transgene Expression in Fibroblast Cells by a Multifunctional Linear-Branched Hybrid Poly(β-Amino Ester) Synthesized through an Oligomer Combination Approach.
Sign Up to like & getrecommendations! Published in 2019 at "Nano letters"
DOI: 10.1021/acs.nanolett.8b04098
Abstract: Delivery of functional genetic materials into fibroblast cells to manipulate the transgene expression is of great significance in skin gene therapy. Despite numerous polymeric gene delivery systems having been developed, highly safe and efficient fibroblast… read more here.
Keywords: poly amino; gene; expression; amino ester ... See more keywords
Co-Delivery of p53 Restored and E7 Targeted Nucleic Acids by Poly (Beta-Amino Ester) Complex Nanoparticles for the Treatment of HPV Related Cervical Lesions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.826771
Abstract: The p53 gene has the highest mutation frequency in tumors, and its inactivation can lead to malignant transformation, such as cell cycle arrest and apoptotic inhibition. Persistent high-risk human papillomavirus (HR-HPV) infection is the leading… read more here.
Keywords: beta amino; hpv; p53; treatment ... See more keywords