Effect of substituents on 3(S)-amino-1-hydroxy-3,4-dihydroquinolin-2(1H)-one: a DFT study
Sign Up to like & getrecommendations! Published in 2019 at "Theoretical Chemistry Accounts"
DOI: 10.1007/s00214-018-2403-0
Abstract: PF04859989 is a potential novel drug designed to attenuate symptoms of Schizophrenia. We analyzed the substitution effect on PF04859989 using three functional, which included the long-range correction. The substituents were both donor and attractor electrons,… read more here.
Keywords: hydroxy dihydroquinolin; dihydroquinolin one; effect; effect substituents ... See more keywords
Synthesis, characterization, and DFT modeling of novel organic compound thin films derived from 2-amino-4-(2-hydroxy-3-methoxyphenyl)-4H-thiazolo[3,2-a][1,3,5]triazin-6(7H)-one
Sign Up to like & getrecommendations! Published in 2020 at "Optical Materials"
DOI: 10.1016/j.optmat.2020.109915
Abstract: Abstract A smooth and effective protocol was proven to produce 2-amino-4-(2-hydroxy-3-methoxy-phenyl)-6-oxo-4H-thiazolo[3,2-a][1,3,5]triazine [2aTZ] via one-pot ternary condensation of easily available mercaptoacetic acid, o-vanillin and dicyandiamide along with ammonium acetate (CH3COONH4) as a catalyst. The chemical structure… read more here.
Keywords: dft; compound thin; amino hydroxy; thiazolo ... See more keywords
Stereoselective Synthesis of Optically Pure 2-Amino-2'-hydroxy-1,1'-binaphthyls.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00800
Abstract: Direct entry to optically pure 2-amino-2'-hydroxy-1,1'-binaphthyl (NOBIN) derivatives by an iron-catalyzed stereoselective oxidative cross-coupling reaction between 2-naphthol and 2-aminonaphthalene with a labile chiral auxiliary is reported. This efficient method offers entry to tailor-designed ( R… read more here.
Keywords: optically pure; pure amino; stereoselective synthesis; amino hydroxy ... See more keywords
A Chiral Iron Disulfonate Catalyst for the Enantioselective Synthesis of 2-Amino-2'-hydroxy-1,1'-binaphthyls (NOBINs).
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c13020
Abstract: A novel type of chiral redox disulfonate iron complex for asymmetric catalysis is reported. The [Fe((Ra)-BINSate)]+ (BINSate = 1,1'-binaphthalene-2,2'-disulfonate) complex effectively promotes the enantioselective oxidative cross-coupling between 2-naphthols (1) and 2-aminonaphthalene derivatives (2), affording optically… read more here.
Keywords: amino hydroxy; iron; binaphthyls nobins; disulfonate ... See more keywords
Stereoselective Allylation of Linear and Chiral β-Amino-α-Hydroxy Aldehydes: Total Syntheses of Tetraacetyl d-lyxo-, d-ribo-, and d-arabino-Phytosphingosines
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DOI: 10.1055/s-0037-1609343
Abstract: The stereoselective allylations of β-amino-α-hydroxy aldehydes are described. Several Lewis acids (BF3·OEt2, SnCl4, TiCl4, ZnCl2, and MgBr2·OEt2) were utilized in the allylations. The allylation of anti-β-NHCbz-α-OTBS substrate mediated by SnCl4 afforded the syn-selective product, while… read more here.
Keywords: tetraacetyl lyxo; total syntheses; hydroxy aldehydes; syntheses tetraacetyl ... See more keywords
The role of a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type receptor modulators in object recognition memory reconsolidation
Sign Up to like & getrecommendations! Published in 2022 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001769
Abstract: Objective Numerous studies suggest that the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type (AMPA) receptor appears to play a central role in mediating brain functions, such as learning and memory. Trafficking of this receptor is related to different long-term memory… read more here.
Keywords: role; amino hydroxy; memory; receptor ... See more keywords
Clinical Review and Prognostic Analysis of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionate Receptor-Associated Encephalitis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.665229
Abstract: Purpose: Autoimmune encephalitis (AE) is a heterogeneous neurological autoimmune disorder associated with cognitive and psychiatric symptoms. It can be divided into several subtypes based on autoantibodies. Anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis (AMPAR-E) is one of the… read more here.
Keywords: hydroxy methyl; encephalitis; amino hydroxy; receptor ... See more keywords