Articles with "amino methyl" as a keyword



Design, synthesis and biological evaluation of 7-(5-((substituted - amino)-methyl)-thiophen-2-yl)-spiro-[chroman-2,4'-piperidin]-4-one hydrochloride analogues as anticancer agents.

Sign Up to like & get
recommendations!
Published in 2021 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2021.104865

Abstract: A series of thirty-one novel 7-(5-((amino)-methyl)-thiophen-2-yl)-spiro-[chroman-2,4'-piperidin]-4-one hydrochloride analogues (Cst 1 - 31) have been designed, synthesized and characterized by 1H NMR, 13C NMR and MS spectral analysis. Here, we evaluated the anticancer potential and biological… read more here.

Keywords: spiro chroman; piperidin one; thiophen spiro; chroman piperidin ... See more keywords
Photo from wikipedia

Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies.

Sign Up to like & get
recommendations!
Published in 2021 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2021.114255

Abstract: 5-Amino-1-methyl quinolinium (5-AMQ) is a potent Nicotinamide N-methyl transferase (NNMT) inhibitor. NNMT is an enzyme that catalyzes the N-methylation of the endogenous substrate nicotinamide, as well as exogenous xenobiotics. NNMT is fundamental to cellular metabolism;… read more here.

Keywords: concentration; rat plasma; rat; amino methyl ... See more keywords
Photo from wikipedia

Effect of ammonia on the kinetics of sulfur dioxide absorption into aqueous 2-amino-2-methyl-1-propanol solutions

Sign Up to like & get
recommendations!
Published in 2017 at "Journal of The Taiwan Institute of Chemical Engineers"

DOI: 10.1016/j.jtice.2017.08.003

Abstract: Abstract Rate constants for the reaction of aqueous 2-amino-2-methyl-1-propanol (AMP)/ammonia (NH3) solutions with SO2 were determined by measuring their SO2 absorption rates. The SO2 absorption characteristics of 30 wt% AMP solutions with added NH3(1, 3, and… read more here.

Keywords: absorption; so2 absorption; aqueous amino; absorption aqueous ... See more keywords
Photo by julienlphoto from unsplash

Spectroscopic and TD-DFT investigations of 4-{[(2-amino-6-methylchromon-3-yl) methylidene]amino}-6-methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one, and its application for photovoltaic devices

Sign Up to like & get
recommendations!
Published in 2018 at "Materials Chemistry and Physics"

DOI: 10.1016/j.matchemphys.2018.06.067

Abstract: Abstract Chemical transformation of 6-methylchromone-3-carbonitrile (1) with 4-amino-6-methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one (2) produced the novel 4-{(2-amino-6-methylchromon-3-yr)methylidene]amino}-6-methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one (AMCMTT). Essential computations were done by the DFT-calculation at B3LYP/6-311G (d,p) geometry to extract the electrostatic potential, electron density, and other related… read more here.

Keywords: amino; thioxo dihydro; triazin one; dihydro triazin ... See more keywords
Photo from wikipedia

Solubility modelling and mixing properties of biologically active 5-amino-3-methyl-1-phenylpyrazole in ten neat solvents from 283.15 K to 318.15 K

Sign Up to like & get
recommendations!
Published in 2017 at "Journal of Molecular Liquids"

DOI: 10.1016/j.molliq.2017.05.124

Abstract: Abstract With the isothermal dissolution equilibrium method, the solid-liquid phase equilibrium for 5-amino-3-methyl-1-phenylpyrazole in ten organic solvents including methanol, ethanol, n -propanol, isopropanol, 2-butanone, acetonitrile, n -butanol, toluene, 1,4-dioxane and isobutanol was established over a… read more here.

Keywords: methyl phenylpyrazole; solubility; amino methyl;
Photo by dilucidus from unsplash

Experimental and theoretical analysis of 2-amino 1-methyl benzimidazole molecule based on DFT

Sign Up to like & get
recommendations!
Published in 2017 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2017.07.055

Abstract: Abstract In this work were shown spectroscopic properties, molecular structure and electronic properties of 2-amino 1 methyl benzimidazole molecule. The theoretical calculations in the title molecule were performed with density functional theory method. Experimental wavenumber… read more here.

Keywords: benzimidazole molecule; molecule; methyl benzimidazole; amino methyl ... See more keywords
Photo from wikipedia

Ab Initio Study of CO2 Capture Mechanisms in Aqueous 2-Amino-2-methyl-1-propanol: Electronic and Steric Effects of Methyl Substituents on the Stability of Carbamate

Sign Up to like & get
recommendations!
Published in 2019 at "Industrial & Engineering Chemistry Research"

DOI: 10.1021/acs.iecr.8b06229

Abstract: Ab initio quantum chemical calculations, combined with the SMD solvation model, have been conducted to reveal CO2 absorption mechanisms and the origin of the reduced stability of carbamate in aqueous solution of 2-amino-2-methyl-1-propanol (AMP). The… read more here.

Keywords: amino methyl; methyl; stability; methyl propanol ... See more keywords
Photo from wikipedia

Comparative Study of CO2 Capture by Aqueous and Nonaqueous 2-Amino-2-methyl-1-propanol Based Absorbents Carried Out by 13C NMR and Enthalpy Analysis

Sign Up to like & get
recommendations!
Published in 2019 at "Industrial & Engineering Chemistry Research"

DOI: 10.1021/acs.iecr.9b00552

Abstract: The CO2 uptake by single 2-amino-2-methyl-1-propanol (AMP) and its blends with 2-(ethylamino)ethanol (EMEA) or N-methyl-2,2′-iminodiethanol (MDEA) has been investigated in both aqueous and nonaqueo... read more here.

Keywords: amino methyl; methyl propanol; methyl; comparative study ... See more keywords
Photo from wikipedia

Effect of Blending Ratio and Temperature on CO2 Solubility in Blended Aqueous Solution of Monoethanolamine and 2-Amino-2-methyl-propanol: Experimental and Modeling Study Using the Electrolyte Nonrandom Two-Liquid Model

Sign Up to like & get
recommendations!
Published in 2020 at "ACS Omega"

DOI: 10.1021/acsomega.0c04046

Abstract: This paper reports the newly measured experimental data for CO2 solubility in a blended aqueous solution of monoethanolamine (MEA) and 2-amino-2-methyl-propanol (AMP) at different amine mixing ratios (MEA/AMP/H2O = 9:21:70, 15:15:70, and 21:9:70 wt %)… read more here.

Keywords: solubility blended; blended aqueous; aqueous solution; co2 solubility ... See more keywords
Photo from wikipedia

Synthesis, spectral analysis, quantum studies, NLO, and thermodynamic properties of the novel 5-(6-hydroxy-4-methoxy-1-benzofuran-5-ylcarbonyl)-6-amino-3-methyl-1H-pyrazolo[3,4-b] pyridine (HMBPP)

Sign Up to like & get
recommendations!
Published in 2022 at "RSC Advances"

DOI: 10.1039/d2ra01469f

Abstract: Ring opening followed by ring closure reactions of 4-methoxy-5-oxo-5H-furo[3,2-g] chromene-6-carbonitrile (1) with 5-amino-3-methyl-1H-pyrazole (2) afforded the novel 5-(6-hydroxy-4-methoxy-1-benzofuran-5-ylcarbonyl)-6-amino-3-methyl-1H-pyrazolo[3,4-b] pyridine (3, HMBPP). The chemical structure of the synthesized compound was established based on elemental analysis and… read more here.

Keywords: novel hydroxy; amino methyl; hydroxy methoxy; analysis ... See more keywords
Photo by louishansel from unsplash

Simple one-pot multicomponent approach to polyfunctionalized 2-amino-1-methyl-6-(methylthio)-5-nitro-4-aryl-1,4-dihydropyridine-3-carbonitriles

Sign Up to like & get
recommendations!
Published in 2017 at "Synthetic Communications"

DOI: 10.1080/00397911.2017.1359845

Abstract: ABSTRACT A series of polyfunctionalized 2-amino-1-methyl-6-(methylthio)-5-nitro-4-aryl-1,4-dihydropyridine-3-carbonitriles have been prepared using a multicomponent condensation reaction between aromatic aldehydes, malononitrile, and (Z) N-methyl-1-(methylthio)-2-nitroethenamine in the presence of Et3N in acetonitrile. GRAPHICAL ABSTRACT read more here.

Keywords: methyl; methylthio nitro; polyfunctionalized amino; methyl methylthio ... See more keywords