Synthesis of N-Substituted 3-Amino-2-pyridones.
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DOI: 10.1021/acs.orglett.2c02189
Abstract: Pyridones are versatile building blocks in organic synthesis and a privileged motif in drug discovery. However, N-substituted 2-pyridones bearing an α-tertiary carbon, cyclopropyl, or heterocycle off of the pyridone nitrogen atom remain challenging to prepare.… read more here.
Keywords: synthesis substituted; chemistry; substituted amino; synthesis ... See more keywords