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   Articles with "amino yne" as a keyword



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Proximity-induced amino-yne reaction for selective MDM4 conjugation via propargylated sulfonium

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recommendations! Published in 2021 at "Chinese Chemical Letters"

DOI: 10.1016/j.cclet.2021.04.015

Abstract: ABSTRACT Whilst most bioorthogonal reactions focus on targeting binding-site cysteine residues, proximity-induced reactivity effect ensures that reaction also occurs at nucleophilic lysine residues. We report one example here that the propargylated-sulfonium center undergoes a nucleophilic… read more here.

Keywords: proximity; propargylated sulfonium; amino yne; reaction ... See more keywords
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Aroylacetylene-Based Amino-Yne Click Polymerization toward Nitrogen-Containing Polymers

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recommendations! Published in 2020 at "Macromolecules"

DOI: 10.1021/acs.macromol.9b02747

Abstract: Synthesis of nitrogen-containing polymers has always been a hot research topic for their broad applications as functional materials. In this work, we established new, spontaneous, and atom-economic... read more here.

Keywords: amino yne; containing polymers; aroylacetylene based; nitrogen containing ... See more keywords

Spontaneous Amino-yne Click Polymerization: A Powerful Tool toward Regio- and Stereospecific Poly(β-aminoacrylate)s.

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recommendations! Published in 2017 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.7b00929

Abstract: Efficient synthesis of poly(enamine)s has been a great challenge because of their poor stability, poor solubility, and low molecular weights. In this work, a spontaneous amino-yne click polymerization for the efficient preparation of poly(enamine)s was… read more here.

Keywords: yne click; amino yne; click polymerization; poly ... See more keywords
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Fast surface immobilization of native proteins through catalyst-free amino-yne click bioconjugation†

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recommendations! Published in 2020 at "Chemical Science"

DOI: 10.1039/d0sc00062k

Abstract: Surface immobilization provides a useful platform for biosensing, drug screening, tissue engineering and other chemical and biological applications. However, some of the used reactions are inefficient and/or complicated, limiting their applications in immobilization. Herein, we… read more here.

Keywords: immobilization; yne click; amino yne; surface immobilization ... See more keywords
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Recent progress in the applications of amino–yne click chemistry

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recommendations! Published in 2021 at "Polymer Chemistry"

DOI: 10.1039/d1py00113b

Abstract: This mini-review summarizes the recent research studies on the application of the amino–yne click reaction in surface immobilization, construction of drug delivery systems, preparation of hydrogel materials and synthesis of functional polymers. read more here.

Keywords: yne click; progress applications; chemistry recent; amino yne ... See more keywords