Novel synthesis of aminoacetonitriles via the selective demethylation of quaternary ammonium salts
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DOI: 10.1016/j.tetlet.2018.03.037
Abstract: Abstract N -Methyl cyclic amines readily formed quaternary ammonium salts upon treatment with iodoacetonitrile in high yields (70–96%). The latter were selectively demethylated by heating in dimethylformamide to give aminoacetonitriles in moderate to good overall… read more here.
Keywords: ammonium salts; aminoacetonitriles via; novel synthesis; quaternary ammonium ... See more keywords