De novo biosynthesis of α‐aminoadipate via multi‐strategy metabolic engineering in Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1301
Abstract: As a non‐protein amino acid, α‐aminoadipate is used in the fields of medicine, chemical engineering, food science, and others. For example, α‐aminoadipate is an important precursor for the production of β‐lactam antibiotics. Currently, the synthesis… read more here.
Keywords: metabolic engineering; biosynthesis; strategy metabolic; multi strategy ... See more keywords
Lysine Catabolism Through the Saccharopine Pathway: Enzymes and Intermediates Involved in Plant Responses to Abiotic and Biotic Stress
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.00587
Abstract: The saccharopine pathway (SACPATH) involves the conversion of lysine into α-aminoadipate by three enzymatic reactions catalyzed by the bifunctional enzyme lysine-ketoglutarate reductase/saccharopine dehydrogenase (LKR/SDH) and the enzyme α-aminoadipate semialdehyde dehydrogenase (AASADH). The LKR domain condenses… read more here.
Keywords: aminoadipate; saccharopine pathway; lysine catabolism; stress ... See more keywords