Synthesis of N, N-Alkylated α-Tertiary Amines by Coupling of α-Aminoalkyltrifluoroborates and Grignard Reagents.
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DOI: 10.1021/acs.orglett.8b01613
Abstract: The cross-coupling of α-aminoalkyltrifluoroborates and Grignard reagents to form N, N-substituted α-tertiary amines (ATAs) is reported. Key to the success of this reaction is the unexpected oxidation of the α-aminoalkyltrifluoroborate to the corresponding iminium cation… read more here.
Keywords: aminoalkyltrifluoroborates grignard; grignard reagents; synthesis alkylated; tertiary amines ... See more keywords