Solid‐phase synthesis of peptide β‐aminoboronic acids
Sign Up to like & getrecommendations! Published in 2019 at "Peptide Science"
DOI: 10.1002/pep2.24072
Abstract: Peptide/boronic acid conjugates are attractive scaffolds for chemical probe discovery and drug design. There are only a few reactions that allow for rapid incorporation of boron into peptides. Herein, we report a new approach towards… read more here.
Keywords: synthesis peptide; peptide; solid phase; peptide aminoboronic ... See more keywords
Primary trifluoroborate-iminiums enable facile access to chiral α-aminoboronic acids via Ru-catalyzed asymmetric hydrogenation and simple hydrolysis of the trifluoroborate moiety
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DOI: 10.1039/d1sc07065g
Abstract: This work describes the first preparation and application of primary trifluoroborate-iminiums (pTIMs) as a new, easily accessible and valuable class of organoboron derivatives. An array of structurally diverse pTIMs was prepared from potassium acyltrifluoroborates in… read more here.
Keywords: primary trifluoroborate; aminoboronic acids; chiral aminoboronic; access chiral ... See more keywords