Industrial landmarks in the development of sustainable production processes for the β-lactam antibiotic key intermediate 7-aminocephalosporanic acid (7-ACA)
Sign Up to like & getrecommendations! Published in 2017 at "Sustainable Chemistry and Pharmacy"
DOI: 10.1016/j.scp.2016.08.001
Abstract: Abstract Reflecting its importance as key intermediate for the large scale manufacture of β-lactam-type antibiotic drugs being widely used in antibacterial therapy, tremendous achievements have been made over the past decades in developing both, economically… read more here.
Keywords: production; key intermediate; chemistry; aminocephalosporanic acid ... See more keywords
Biochemical characterization of an acetylesterase from Bacillus subtilis and its application for 7-aminocephalosporanic acid deacetylation
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DOI: 10.3389/fmicb.2023.1164815
Abstract: Deacetyl-7-aminocephalosporanic acid (D-7-ACA), which could be converted from 7-aminocephalosporanic acid (7-ACA), is a crucial starting material that is used for synthesizing industrial semisynthetic β-lactam antibiotics. Enzymes involved in the conversion from 7-ACA to D-7-ACA present… read more here.
Keywords: estsj; aminocephalosporanic acid; bacillus subtilis; acid ... See more keywords