Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1909831116
Abstract: Significance The cryo-electron microscopy high-resolution structures of the wild-type ribosome of the human pathogen Pseudomonas aeruginosa and its uL6 rProtein mutant, isolated from a cystic fibrosis (CF) patient, shed light on the link between a… read more here.
Keywords: pseudomonas aeruginosa; initiation; microscopy; binding site ... See more keywords
Early in vitro development of daptomycin non-susceptibility in high-level aminoglycoside-resistant Enterococcus faecalis predicts the efficacy of the combination of high-dose daptomycin plus ampicillin in an in vivo model of experimental endocarditis
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DOI: 10.1093/jac/dkx016
Abstract: Background Previous studies showed development of daptomycin non-susceptibility (DNS: MIC >4 mg/L) in Enterococcus faecalis infections. However, no studies have assessed the efficacy of the combination of daptomycin/ampicillin against E. faecalis strains developing DNS in the… read more here.
Keywords: high level; faecalis; daptomycin ampicillin; aminoglycoside resistant ... See more keywords
Identification of major sequence types among aminoglycoside resistant Staphylococcus aureus and Staphylococcus epidermidis strains isolated from clinical samples
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Microbiology"
DOI: 10.18502/ijm.v14i3.9760
Abstract: Background and Objectives: Aminoglycosides have been widely used for treating severe staphylococcal infections. Production aminoglycoside modifying enzymes (AMEs) is the main mechanism of resistance to this antibiotic. The aim of this study was to determine… read more here.
Keywords: epidermidis; staphylococcus; sequence; aminoglycoside resistant ... See more keywords