Synthesis, antimicrobial and cytotoxic activities, and molecular docking studies of N-arylsulfonylindoles containing an aminoguanidine, a semicarbazide, and a thiosemicarbazide moiety.
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DOI: 10.1016/j.ejmech.2019.01.038
Abstract: Thirty-six N-arylsulfonyl-3-substituted indoles were designed and synthesized by combining the N-arylsulfonylindoles with aminoguanidine, semicarbazide, and thiosemicarbazide, respectively. Their antibacterial activities were screened, and cytotoxic activities were evaluated. The results showed that aminoguanidines (6) exhibited much… read more here.
Keywords: aminoguanidine semicarbazide; docking studies; cytotoxic activities; semicarbazide thiosemicarbazide ... See more keywords