Clinical uses of 5-aminolaevulinic acid in photodynamic treatment and photodetection of cancer: A review.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.06.008
Abstract: ALA-mediated Photodynamic Therapy (ALA-PDT) is one of the most promising fields in Photodynamic therapy (PDT) research for cancer treatment. 5-aminolaevulinic acid (ALA) is the prodrug of the photosensitiser Protoporphyrin IX (PpIX). After ALA administration, cells… read more here.
Keywords: ala pdt; ala; treatment; clinical uses ... See more keywords
Hydroxypyridinone and 5-Aminolaevulinic Acid Conjugates for Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b00346
Abstract: Photodynamic therapy (PDT) is a promising treatment strategy for malignant and nonmalignant lesions. 5-Aminolaevulinic acid (ALA) is used as a precursor of the photosensitizer, protoporphyrin IX (PpIX), in dermatology and urology. However, the effectiveness of… read more here.
Keywords: hydroxypyridinone; ppix; photodynamic therapy; aminolaevulinic acid ... See more keywords
In order for the light to shine so brightly, the darkness must be present—why do cancers fluoresce with 5-aminolaevulinic acid?
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Cancer"
DOI: 10.1038/s41416-019-0516-4
Abstract: Photodynamic diagnosis and therapy have emerged as a promising tool in oncology. Using the visible fluorescence from photosensitisers excited by light, clinicians can both identify and treat tumour cells in situ. Protoporphyrin IX, produced in… read more here.
Keywords: order light; aminolaevulinic acid; cancer; shine brightly ... See more keywords
Case report: Acne vulgaris treatment with 5-Aminolaevulinic acid photodynamic therapy and adalimumab: a novel approach
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1187186
Abstract: Acne vulgaris is a common skin condition that affects a large proportion of teenagers and young adults. Despite the availability of various treatment options, many patients experience inadequate relief or intolerable side effects. Photodynamic therapy… read more here.
Keywords: acne vulgaris; photodynamic therapy; aminolaevulinic acid; treatment ... See more keywords
Methyl Aminolaevulinic Acid versus Aminolaevulinic Acid Photodynamic Therapy of Actinic Keratosis with Low Doses of Red-Light LED Illumination: Results of Long-Term Follow-Up
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10123218
Abstract: Photodynamic therapy (PDT) treatment for multiple actinic keratosis (AK) has been found effective when lower doses of red light were used with methyl aminolaevulinic acid (MAL). The aim of this study was to compare the… read more here.
Keywords: long term; doses red; acid; red light ... See more keywords
5-aminolaevulinic acid-based photodynamic therapy inhibits ultraviolet B-induced skin photodamage
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.31583
Abstract: To evaluate the photoprotective effect of 5-aminolaevulinic acid-based photodynamic therapy (ALA-PDT) on ultraviolet B (UVB)-induced skin photodamage. In vivo experiments, the dorsal skin of hairless mice were treated with ALA-PDT or saline-PDT, and then exposed… read more here.
Keywords: ala pdt; acid based; pdt; aminolaevulinic acid ... See more keywords