Mannich aminomethylation of flavonoids and anti-proliferative activity against breast cancer cell
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Papers"
DOI: 10.1007/s11696-018-0402-1
Abstract: We herein report Mannich aminomethylation of variously structural flavonoids and their biological evaluation against human breast cancer cell. Mannich reaction showed that substitution at C-6 position depends on amine basicity and C-ring feature of flavonoids.… read more here.
Keywords: anti proliferative; aminomethylation; breast cancer; cancer cell ... See more keywords
Aminomethylation of Aryl Halides using α-Silylamines Enabled by Ni/Photoredox Dual Catalysis.
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DOI: 10.1021/acscatal.7b01973
Abstract: A protocol for the aminomethylation of aryl halides using α-silylamines via Ni/photoredox dual catalysis is described. The low oxidation potential of these silylated species enables facile single electron transfer (SET) oxidation of the amine followed… read more here.
Keywords: halides using; aminomethylation; catalysis; aryl halides ... See more keywords
Photoredox catalysed reductive aminomethylation of quaternary benzophenanthridine alkaloids.
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DOI: 10.1080/14786419.2022.2092732
Abstract: Reduction of C = N double bond is the most important phase I metabolism process of quaternary benzophenanthridine alkaloids (QBAs). Inspired by the NADPH mediated reduction in QBAs, a visible-light promoted reductive aminomethylation of QBAs for synthesis… read more here.
Keywords: aminomethylation; benzophenanthridine alkaloids; reductive aminomethylation; quaternary benzophenanthridine ... See more keywords