Inhibitors of ER aminopeptidase 1 and 2: from design to clinical application.
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DOI: 10.2174/0929867325666180214111849
Abstract: Endoplasmic Reticulum aminopeptidase 1 and 2 are two homologous enzymes that help generate peptide ligands for presentation by Major Histocompatibility Class I molecules. Their enzymatic activity influences the antigenic peptide repertoire and indirectly controls adaptive… read more here.
Keywords: aminopeptidase design; chemistry; inhibitors aminopeptidase; design clinical ... See more keywords