Aminopeptidase N Inhibitors as Pointers for Overcoming Antitumor Treatment Resistance
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179813
Abstract: Aminopeptidase N (APN), also known as CD13 antigen or membrane alanyl aminopeptidase, belongs to the M1 family of the MA clan of zinc metallopeptidases. In cancer cells, the inhibition of aminopeptidases including APN causes the… read more here.
Keywords: aminopeptidase; treatment resistance; cancer; aminopeptidase inhibitors ... See more keywords
In Silico Screening for Novel Leucine Aminopeptidase Inhibitors with 3,4-Dihydroisoquinoline Scaffold
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25071753
Abstract: Cancers are the leading cause of deaths worldwide. In 2018, an estimated 18.1 million new cancer cases and 9.6 million cancer-related deaths occurred globally. Several previous studies have shown that the enzyme, leucine aminopeptidase is… read more here.
Keywords: leucine aminopeptidase; aminopeptidase; novel leucine; silico screening ... See more keywords