Articles with "aminopeptidases erap1" as a keyword



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The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1066483

Abstract: Introduction Critical steps in Major Histocompatibility Complex Class I (MHC-I) antigen presentation occur in the endoplasmic reticulum (ER). In general, peptides that enter the ER are longer than the optimal length for MHC-I binding. The… read more here.

Keywords: synergize self; aminopeptidases erap1; erap2 synergize; erap1 erap2 ... See more keywords