Dinuclear zinc-catalyzed asymmetric Friedel-Crafts alkylation/cyclization of 3-aminophenols with α,α-dicyanoolefins.
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DOI: 10.1039/d1cc04177k
Abstract: An enantioselective Friedel-Crafts alkylation/cyclization tandem reaction of 3-aminophenols with α,α-dicyanoolefins has been performed successfully using a chiral dinuclear zinc catalyst, leading to a range of chiral 2-amino-4H-chromenes (up to 98% yield and >99% ee). To… read more here.
Keywords: crafts alkylation; aminophenols dicyanoolefins; dinuclear zinc; zinc ... See more keywords