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Organocatalytic Asymmetric Synthesis of Tetrahydroquinolines from ortho-Aminophenyl para-Quinone Methides.

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Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c02874

Abstract: The asymmetric catalytic [4 + 2] cycloannulation of ortho-aminophenyl p-QMs with different types of alkenes for the construction of tetrahydroquinolines containing three contiguous stereogenic centers was developed. This is the first example of catalytic asymmetric… read more here.

Keywords: synthesis tetrahydroquinolines; ortho aminophenyl; organocatalytic asymmetric; aminophenyl para ... See more keywords