Silylated iminophosphonates: Novel reactive synthons for the preparation of fluorinated aminophosphonates and aminophosphonic acids
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.07.075
Abstract: Abstract A convenient synthetic approach towards previously unknown N- and N,O-silylated α-iminophosphonates bearing fluoroalkyl groups at the imine C atom was developed. The synthetic potential of the compounds was demonstrated by their easy functionalization and… read more here.
Keywords: iminophosphonates novel; aminophosphonic acids; reactive synthons; silylated iminophosphonates ... See more keywords
Recent progress in asymmetric synthesis of aminophosphonic acids mediated by chiral sulfinyl auxiliary
Sign Up to like & getrecommendations! Published in 2017 at "Pure and Applied Chemistry"
DOI: 10.1515/pac-2016-1023
Abstract: Abstract This account outlines the recent results on our strategy of the diastereoselective asymmetric synthesis of aminophosphonic acids (APs) using enantiomeric sulfinimines as chirality inducing reagents. Three important topics are discussed: (a) application of a… read more here.
Keywords: synthesis aminophosphonic; aminophosphonic acids; asymmetric synthesis; recent progress ... See more keywords
Novel α-Aminophosphonates and α-Aminophosphonic Acids: Synthesis, Molecular Docking and Evaluation of Antifungal Activity against Scedosporium Species
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DOI: 10.3390/molecules27123886
Abstract: The Scedosporium genus is an emerging pathogen with worldwide prevalence and high mortality rates that gives multidrug resistance to antifungals; therefore, pharmacological alternatives must be sought for the treatment of diseases caused by this fungus.… read more here.
Keywords: antifungal activity; compound; novel aminophosphonates; scedosporium ... See more keywords