Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors.
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DOI: 10.1021/acs.jmedchem.2c01346
Abstract: The receptor tyrosine kinase AXL is a promising target for anticancer drug discovery. Herein, we describe the discovery of 3-aminopyrazole derivatives as new potent and selective AXL kinase inhibitors. One of the representative compounds, 6li,… read more here.
Keywords: new potent; aminopyrazole derivatives; axl; discovery aminopyrazole ... See more keywords