Radiolabeled Aminopyrazoles as Novel Isoform Selective Probes for pJNK3 Quantification.
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DOI: 10.1021/acsmedchemlett.2c00278
Abstract: The c-Jun N-terminal kinase 3 (JNK3) is a stress-activated kinase primarily expressed in the brain and implicated as an early mediator of neuronal apoptosis. We sought to develop a PET tracer to visualize pathological JNK3… read more here.
Keywords: jnk3 activation; jnk3; radiolabeled aminopyrazoles; aminopyrazoles novel ... See more keywords