Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: Synthesis, characterization, crystal structure and bioactivity properties.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103134
Abstract: In this work, the synthesis, crystal structure, characterization, and enzyme inhibition effects of the novel a series of 2-aminopyridine liganded Pd(II) N-heterocyclic carbene (NHC) complexes were examined. These complexes of the Pd-based were synthesized from… read more here.
Keywords: crystal structure; liganded heterocyclic; aminopyridine liganded; inhibition ... See more keywords
Electrochemical studies of 2-aminopyridine on nanocrystalline Zn Ni alloy electrodeposition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2019.01.038
Abstract: Abstract Nanocrystalline alloy exhibit superior characteristics that are not typically found in conventional coating and its formation is usually induced by additives. However, the influence mechanism of additives on the electrodeposition process was rare to… read more here.
Keywords: electrochemical studies; electrodeposition; nanocrystalline alloy; adsorption ... See more keywords
4-Aminopyridine is a promising treatment option for patients with gain-of-function KCNA2-encephalopathy
Sign Up to like & getrecommendations! Published in 2021 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aaz4957
Abstract: Description 4-Aminopyridine is a potential therapeutic option for a subgroup of patients with KCNA2-encephalopathy and gain-of-function variants. Targeting the K+ey current Gain-of-function (GOF) mutations in the potassium channel Kv1.2 cause a subtype of developmental KCNA2-encephalopathy,… read more here.
Keywords: medicine; treatment; kcna2 encephalopathy; aminopyridine ... See more keywords
Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice
Sign Up to like & getrecommendations! Published in 2020 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.264471
Abstract: Oral 4-aminopyridine (4-AP) is clinically used for symptomatic relief in multiple sclerosis and we recently demonstrated that systemic 4-AP had previously unknown clinically-relevant effects after traumatic peripheral nerve injury including the promotion of re-myelination, improvement… read more here.
Keywords: injury mice; aminopyridine; nerve; functional recovery ... See more keywords