Incorporation of Trifluoromethyltriazoline in the Side Chain of 4‐Aminoquinolines: Synthesis and Evaluation as Antiplasmodial Agents
Sign Up to like & getrecommendations! Published in 2023 at "ChemMedChem"
DOI: 10.1002/cmdc.202200653
Abstract: Reported herein is the identification of a novel class of 4‐aminoquinoline‐trifluormethyltriazoline compounds as possible antiplasmodial agents. The compounds were accessed through a silver‐catalyzed three‐component reaction of trifluorodiazoethane with in situ generated Schiff base from corresponding quinolinylamine… read more here.
Keywords: chain aminoquinolines; side chain; incorporation trifluoromethyltriazoline; aminoquinolines synthesis ... See more keywords