5-Aminosalicylic Acid Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats by Increasing the Expression of Nur77
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0525-5
Abstract: The aim of this study is to investigate the effect of 5-aminosalicylic acid (5-ASA) on monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) in rats and its molecular mechanism. Sixty male Sprague–Dawley rats (250–300 g) were evenly randomized… read more here.
Keywords: pah group; asa; group; pulmonary arterial ... See more keywords
Control releasing 5-aminosalicylic acid using pH-sensitive hydrogel with novel albumin cross-linker
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Inclusion Phenomena and Macrocyclic Chemistry"
DOI: 10.1007/s10847-018-0863-4
Abstract: Intelligent drug delivery systems are growing and changing too fast, these systems usually show a proper response at the proper time to one or several environmental factors. In the current research a biodegradable drug delivery… read more here.
Keywords: hydrogel; aminosalicylic acid; cross linker; albumin ... See more keywords
A theoretical investigation on decarboxylation mechanism of antibiotic para-aminosalicylic acid to highly toxic form meta-aminophenol
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DOI: 10.1007/s11224-020-01676-9
Abstract: The antibiotic para-aminosalicylic acid (PAS) is decomposed into its decarboxylated product, meta-aminophenol, with a series of toxicity symptoms including hemolytic anemia. The present trial investigates the decarboxylation mechanism of PAS, along with an in-detail assessment… read more here.
Keywords: mechanism; antibiotic para; decarboxylation; aminosalicylic acid ... See more keywords
Drug‐drug cocrystals of antituberculous 4‐aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2016.12.016
Abstract: Abstract Experimental multistage cocrystal screening of the antituberculous drug 4‐aminosalicylic acid (PASA) has been conducted with a number of coformers (pyrazinamide (PYR), nicotinamide (NAM), isonicotinamide (iNAM), isoniazid (INH), caffeine (CAF) and theophylline (TPH)). The crystal… read more here.
Keywords: pasa; crystal structures; drug; aminosalicylic acid ... See more keywords
Functionalized biogenic hydroxyapatite with 5-aminosalicylic acid – Sorbent for efficient separation of Pb2+ and Cu2+ ions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of environmental chemical engineering"
DOI: 10.1016/j.jece.2017.07.027
Abstract: Abstract The biogenic hydroxyapatite (BHAP), obtained by proper treatment of bovine bones, was functionalized with 5-aminosalicylic acid (5-ASA). The coordination of 5-ASA to the surface of BHAP leads to the charge transfer (CT) complex formation… read more here.
Keywords: pb2; biogenic hydroxyapatite; aminosalicylic acid; bhap ... See more keywords
Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid.
Sign Up to like & getrecommendations! Published in 2022 at "ACS infectious diseases"
DOI: 10.1021/acsinfecdis.2c00433
Abstract: Apart from the SARS-CoV-2 virus, tuberculosis remains the leading cause of death from a single infectious agent according to the World Health Organization. As part of our long-term research, we prepared a series of hybrid… read more here.
Keywords: compound; acid; activity; aminosalicylic acid ... See more keywords
Characteristics, Properties and Analytical/Bioanalytical Methods of 5-Aminosalicylic Acid: A Review.
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DOI: 10.1080/10408347.2020.1848516
Abstract: Five-aminosalicylic acid (5-ASA) is an anti-inflammatory drug indicated in the treatment of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Among the analytical methods of quantification of 5-ASA described in the literature, the… read more here.
Keywords: characteristics properties; bioanalytical methods; analytical bioanalytical; aminosalicylic acid ... See more keywords
Modern use of 5-aminosalicylic acid compounds for ulcerative colitis
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2019.1666101
Abstract: ABSTRACT Introduction: For 30 years, 5-aminosalicylic acid (5-ASA) has been the backbone of therapeutic management in patients with ulcerative colitis (UC). In the biologic era, it still remains the treatment of choice in mild-to-moderate UC.… read more here.
Keywords: use aminosalicylic; aminosalicylic acid; modern use; ulcerative colitis ... See more keywords
Effect of Reaction Time and Stability Properties of Gold Nanoparticles Synthesized by p-Aminobenzoic Acid and p-Aminosalicylic Acid
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DOI: 10.22146/ijc.44674
Abstract: In this work, we determined the influenced of the reaction time at the synthesis of gold nanoparticles (AuNPs) by p-aminosalicylic acid and p-aminobenzoic acid as reducing agent. Besides working as a reducing agent, the p-aminobenzoic… read more here.
Keywords: acid aminosalicylic; reaction time; gold nanoparticles; aminobenzoic acid ... See more keywords
5-Aminosalicylic acid aggravates colitis mimicking exacerbation of ulcerative colitis
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DOI: 10.5217/ir.2018.00015
Abstract: Ulcerative colitis (UC) is one of the major clinical phenotypes of inflammatory bowel diseases. Although 5-aminosalicylic acid (5-ASA) is widely used for UC and its efficacy and safety have been demonstrated, a few patients paradoxically… read more here.
Keywords: acid aggravates; aggravates colitis; colitis; aminosalicylic acid ... See more keywords
Colitis and Crohn’s Foundation (India) consensus statements on use of 5-aminosalicylic acid in inflammatory bowel disease
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DOI: 10.5217/ir.2019.09176
Abstract: Despite several recent advances in therapy in inflammatory bowel disease (IBD), 5-aminosalicylic acid (5-ASA) therapy has retained its place especially in ulcerative colitis. This consensus on 5-ASA is obtained through a modified Delphi process, and… read more here.
Keywords: inflammatory bowel; aminosalicylic acid; bowel disease;